Amides are among the most ubiquitous functional groups in organic chemistry, forming the backbone of peptides and playing a vital role in pharmaceutical, synthetic and materials chemistry. Their ...

The amide bond can be activated for cleavage under mild, neutral conditions by chemical derivatization, a British group has demonstrated (Angew. Chem. Int. Ed., DOI: 10.1002/anie.201107117). Amide ...

Please provide your email address to receive an email when new articles are posted on . By week 16, both treatment groups saw similar reductions in melasma severity from baseline. Cysteamine isobionic ...

Extending or trimming the length of a drug molecule’s carbon backbone by just a couple of atoms can significantly alter its activity, even if nothing else in the structure changes. So reactions that ...

Pfizer's Paxlovid looks very promising in fighting COVID. It also provides a good opportunity to learn about how enzyme inhibitors work. For masochists only. Although different chemists may have other ...