Early CAR T cell expansion is associated with both therapeutic activity and inflammatory toxicity, such as cytokine release syndrome and neurotoxicity. Routine flow cytometry can reliably track ...

Liquid biopsy-based prediction of clinical benefit from immune checkpoint inhibitors in advanced biliary tract cancer. This is an ASCO Meeting Abstract from the 2024 ASCO Annual Meeting I. This ...

Conventional cell- and bead-based assays can be time-consuming, manual procedures providing only semi-quantitative data. Using high-content analysis systems to obtain object-based, quantitative data ...

With the ever-increasing pace of biological research, there is a plethora of headlines describing novel and fascinating discoveries about our natural world. What’s easy to overlook, however, is the ...

Harmonizing immunophenotyping assay designs facilitates integrating findings across trials, enabling biomarker identification and validation, revealing cohort-specific features and drug mechanisms as ...

B-cell maturation antigen (BCMA) is encoded by the TNFRSF17 gene found on the short arm of chromosome 16. BCMA is a type III transmembrane glycoprotein primarily expressed on the surface of myeloma ...

Functional Characterization and a Real-World Clinical Laboratory Pilot of the Foundation for the National Institutes of Health Circulating Tumor DNA Quality Control Materials A total of 871 patient ...

Daniel Hui, PhD, Associate Director of Analytical Development at Tmunity Therapeutics recently discussed the components of its “CAR-T toolbox.” Scientists developing chimeric antigen receptor (CAR) T ...

Adoptive cell therapies, also known as cellular immunotherapies, are a personalized treatment strategy that involves engineering patients’ immune cells to recognize and attack their own tumors. This ...