The new CRISPR platform, called ΨDNA, reprograms Cas12 nucleases to recognize and act on RNA using a DNA-based guide scaffold ...

02 February 2023, Hesse, Marburg: A press spokeswoman points to a plasmid model at the Görzhausen I Biontech site. Photo: Sebastian Christoph Gollnow/dpa (Photo by Sebastian Christoph Gollnow/picture ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the right times. RNA is one such molecule; the sequences for different proteins ...

While the central dogma of molecular biology outlines the linear flow of genetic information from DNA to RNA to proteins (black lines), glycomics introduces a “3rd code of life”—glycans—that operates ...

"DNA guides are far cheaper and easier to manufacture than RNA guides, and they are far more stable," Jain said. "While RNA molecules degrade quickly, DNA can remain intact for long periods." Together ...

PlantGFM created synthetic plant DNA that tobacco cells copied into RNA, with some sequences producing detectable proteins in ...

Researchers have found surprising links that show that Neanderthal ancestry influences our immune system today in ways more nuanced than previously recognized. Their work is published in the journal ...

Chemical structure of guanine, showing its double-ring purine structure and the functional groups involved in hydrogen bonding with cytosine. (Image: Public Domain) Guanine has the chemical formula ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.