Rockefeller University scientists show that a protein crucial for the accurate copying of DNA during cell division serves as a toolbelt from which the correct proteins are retrieved to enable DNA ...
When a dividing cell duplicates its genetic material, a molecular machine called a sliding clamp travels along the DNA double helix, tethering the proteins that perform the replication. Researchers ...
The process of DNA replication relies on the coordinated action of a ring‐shaped sliding clamp and its specialised loader complexes. Sliding clamps, typified by proliferating cell nuclear antigen ...