The inhibition of pathological protein-protein interactions is a promising approach for treating a large number of diseases, including many forms of cancer. A team of researchers has now developed a ...
Chemists from Scripps Research and the University of California, Los Angeles, have developed methods for the precise, flexible modification of a broad class of chemical compounds called bicyclic ...
AstraZeneca will partner with Bicycle Therapeutics to develop respiratory, cardiovascular, and metabolic disease treatments based on Bicycle’s proprietary bicyclic peptide (Bicycle ®) product platform ...
Bicyclic peptides have spurred some multimillion-dollar deals in recent years, as drug developers begin to exploit the peptides’ power to target and bind proteins. Now, researchers led by Christoph ...
Sequential intravesical gemcitabine and docetaxel versus bacillus Calmette-Guérin for the treatment of high-risk, treatment-naïve, non-muscle invasive bladder cancer. This is an ASCO Meeting Abstract ...
Cytokinetics Inc. has identified bicyclic piperazinones with the ability to modulate skeletal muscle contractility reported to be useful for the treatment of amyotrophic lateral sclerosis, spinal ...
CAMBRIDGE, United Kingdom & CAMBRIDGE, Mass.--(BUSINESS WIRE)--Bicycle Therapeutics, a biotechnology company pioneering a new class of therapeutics based on its proprietary bicyclic peptide (Bicycle ® ...
Transactions of the American Mathematical Society, Vol. 358, No. 6 (Jun., 2006), pp. 2579-2610 (32 pages) We examine some properties of bicyclic algebras, i.e. the tensor product of two cyclic ...
Roche’s recent spate of billion-dollar plus alliances has continued with a deal with UK biotech Bicycle Therapeutics – worth up to $1.7 billion – in the area of cancer immunotherapy. The agreement is ...
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