That would make drinking less pleasurable – and decrease the desire to keep doing it. However, there seems to be more to caffeine's dopamine blocking than just counteracting what alcohol does.

There's also evidence that caffeine's effects on adenosine and dopamine receptors may have long term benefits like reducing the risk of Parkinson's, Alzheimer's, and some types of cancer.

“That is a response to that lack of vasoconstriction.” Caffeine is a psychostimulant that works by blocking the adenosine receptors in the brain, which are linked to sleep, memory and learning.

Learn how caffeine affects Parkinson's disease prevention and treatment. New research uncovers both protective benefits and treatment limitations.

“The effects of caffeine are to block this sleep factor adenosine and also through by preventing adenosine from inhibiting this dopamine receptor.” ...

A 2015 study showed that caffeine does not directly stimulate dopamine production. Instead, it increases the number of available dopamine receptors in the brain.

Caffeine stimulates the release of hormones adrenaline, cortisol, and epinephrine. Caffeine also increases the levels of neurotransmitters dopamine and norepinephrine.

By blocking adenosine receptors, caffeine may indirectly increase dopamine release, which could potentially protect against Parkinson’s disease.” However, there are a number of theories.

When caffeine binds to adenosine receptors, it promotes the release of excitatory neurotransmitters, such as norepinephrine and dopamine, while also inhibiting the secretion of inhibitory ...

The binding of adenosine to receptors can promote feelings of sleepiness by slowing down the release of neurotransmitters that play crucial roles in boosting wakefulness, like dopamine and ...

Caffeine is a psychostimulant that works by blocking the adenosine receptors in the brain, which are linked to sleep, memory and learning.