Drug discovery is shifting from static snapshots to moving pictures. Instead of inferring how medicines work from end results ...
A research team of the University Medical Center Mainz has succeeded in observing for the first time how G protein-coupled ...
Many people are familiar with histamine, a biological molecule that serves as a key driver of allergic reactions and other ...
New Cell-Based Assays Support Drug Discovery Across the Amylin Receptor Family STATE COLLEGE, PA, UNITED STATES, ...
Scientists at École Polytechnique Fédérale Lausanne (EPFL), and at UNIL-CHUV, University Hospital Lausanne (CHUV) and University of Lausanne (UNIL) have developed a computational method to create ...
One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...
Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...
Blockbuster anti-obesity drugs like Ozempic and Wegovy have become household names in the past few years. They work by activating the glucagon-like peptide 1 receptor (GLP-1R) to stimulate insulin ...
Phase II Trial of Nivolumab Plus Doxorubicin, Vinblastine, Dacarbazine as Frontline Therapy in Older Adults With Hodgkin Lymphoma Colorectal cancer (CRC) remains a major global health burden, being ...
Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.