Using patents published by leading pharmaceutical companies in the 2000–2010 period, the molecular properties of the compounds acting at the drug targets pursued have been analysed. Over the past ...

This Analysis article describes the compilation and analysis of combined data on the attrition of drug candidates from AstraZeneca, Eli Lilly and Company, GlaxoSmithKline and Pfizer. The analysis ...

Researchers have developed a compound that relieves pain in mice but doesn't affect the brain, thereby avoiding mind-altering side effects and abuse potential. The custom-designed molecule, derived ...

Honghui Hu of Wanhuida Intellectual Property considers the impact of the structure-activity relationship on the inventiveness assessment of pharmaceutical compounds Bayer Intellectual Property GmbH ...