Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...

Layer 6b, the deepest layer of the mammalian brain's cortex, has recently been the focus of numerous neuroscience studies. Despite the interesting findings gathered in recent years, the role of this ...

For decades, neuroscientists have thought about communication between the cerebral cortex and the basal ganglia in a fairly ...

The outer regions of the brain, the cortex, have specific layers of different cells - neurons - that are similarly ordered among all mammals, from tiny mouse brains to huge elephant brains. However, ...

“It is an outstanding example of circuit analysis and a real experimental tour de force,” said neuroscientist Massimo Scanziani of the University of California, San Diego, who was not involved in the ...

A new approach to fMRI scanning offers a three-dimensional look at brain activation. fMRI is already a 3D technique, of course, but in the case of the cerebral cortex - which is what the great ...

The outer regions of the brain, the cortex, have specific layers of different cells—neurons—that are similarly ordered among all mammals, from tiny mouse brains to huge elephant brains. However, the ...

A new study explains apical hypercontextualisation and how psychedelics alter layer V pyramidal neuron processing.

A new spatial transcriptomic approach captures the regulation of splicing and polyadenylation sites during pubescent brain development at near-single-cell resolution. An international collaboration, ...