Immunotherapy using modified chimeric antigen receptor (CAR) T cells has improved survival rates for pediatric patients with relapsed and recurrent leukemia. However, these therapies are not as ...

CAR-T cell therapy has emerged as a transformative approach in treating B cell malignancies and multiple myeloma. However, this approach is in desperate need of refinement. While attacking tumor cells ...

(MEMPHIS, Tenn. – November 30, 2023) Immunotherapy using modified chimeric antigen receptor (CAR) T cells has greatly improved survival rates for pediatric patients with relapsed and recurrent ...

An artificial intelligence–driven transfer learning strategy enabled the discovery of a novel indolopyridine-based small ...

New approach recruits the body’s immune system to attack glioblastoma while reducing treatment-related toxicity.

Current cell therapies like CAR-T cells lack the precision to distinguish between healthy and diseased tissue, leading to limited effectiveness and potential side effects. One of the most significant ...

Cytokines are key to immune regulation. Their extensive impact on human biology and disease has led to their long-term therapeutic use in treating cancer and a range of other diseases. Interleukin-2 ...

Autoimmune diseases result from a complex interaction of immune system imbalances, marked by a breakdown in self-tolerance and sustained inflammation. At the core of this dysregulation are ...