Scientists have long known that dopamine helps the brain learn from rewards, but a new computational model shows how for people with schizophrenia this learning system can break down and ...

Researchers have found statistically significant links between a gene tied to schizophrenia risk and poorer cognitive ...

Researchers at the University of Illinois Urbana-Champaign have traced a genetic mutation found in psychosis patients to a specific breakdown in the brain’s learning machinery, offering one of the ...

Prof. Alex Nord, right and graduate student Tracy Warren have discovered genetic variants linked to some symptoms of schizophrenia that are currently hard to treat. The work could lead to new insights ...

Schizophrenia risk may reflect two brain pathways with different cortical and subcortical balance. Early language learning relies more on subcortical systems; later learning engages cortical control.

Our understanding of schizophrenia has increased greatly in recent years, as studies of large groups of people have identified a multitude of genetic variants that increase a person's risk of the ...

A genetic postmortem analysis of the brains of patients with schizophrenia suggests dysfunction of dopamine receptors in the caudate nucleus may cause the disorder. Investigators identified a ...

It has long been known as the arbiter of reward in the brain, but recent findings could upend this classic theory of dopamine ...

A finding by a McGill-led team of neuroscientists could open doors to new treatments for a range of psychiatric and neurological disorders attributed to dysfunctions in specific dopamine pathways. For ...

The caudate nucleus (green) is a subcortical brain region located in the striatum. The striatum is one of several neural structures that make up the basal ganglia (colored regions) located below the ...