Surface plasmon resonance (SPR) detectors monitor molecular interactions without labels and in real time. SPR imaging (SPRi) has the additional advantage of increased throughput since it monitors ...

A team of University of Michigan researchers is developing a new anti-cancer drug that is absorbed through the gut's lymphatic system rather than blood vessels, potentially outmaneuvering the ...

Biopharmaceutical drug absorption encompasses the complex interplay of physicochemical, biological and formulation factors that determine how an orally administered therapeutic agent moves from its ...

To test the efficacy of the patch, the team loaded the EW-MNs with rivastigmine (a drug commonly used to treat Alzheimer's and Parkinson's disease). In animal studies using guinea pigs, the ...

CAMBRIDGE, Mass.--(BUSINESS WIRE)--Vivtex Corporation, a pre-clinical biotechnology company focused on the oral delivery of biologics into systemic blood circulation or localized into GI tissue, ...

Passive diffusion plays an essential role in oral absorption of drugs through the gastrointestinal tract, penetration across the blood-brain barrier to reach Central Nervous System disease targets, ...

In this interview, Karl Box discusses how particle drift analysis using flux tools improves oral drug absorption in pharmaceutical research. Can you tell us about Pion’s Rainbow Dynamic Dissolution ...

In this interview, News Medical talks to Patrick D. Sinko about the role of particle size, dose, and confinement parameters in advancing drug absorption modeling. Could you explain what a boundary ...

Monolayers of cancer-derived cell lines are widely used in the modelling of the gastrointestinal (GI) absorption of drugs and in oral drug development. However, they do not generally predict drug ...

Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematized review revealed critical gaps in methodology. Of 18 original research articles selected ...

The NMR and Drug Metabolism Core has developed rapid and efficient approaches to investigate metabolism, metabolic stability, pharmacokinetics (PK), and chemical structure identification of small ...