Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete ...

Organoids—tiny, lab-grown 3D clusters of cells—are a useful tool for studying organ development, disease, and drug responses. These miniature organs-in-a-dish are powerful, but they’re not perfect: ...

Toward the goal of elucidating endocrine system aging mechanisms, this study establishes the first single-cell aging atlas across multiple endocrine organs. The research reveals conserved aging ...

Hormone systems, which control diverse physiological functions, have been extensively studied, yet consistent rules underlying these systems remain elusive. Here we identify unifying design principles ...

Immunofluorescence image of the pancreatic islets of a 50-year-old-female without diabetes. This individual had 54% beta cells (GREEN), 9% delta cells (WHITE) and 37% alpha cells (RED). Diabetes is ...

Remarkable advances in protocol development have been achieved to manufacture insulin-secreting islets from human pluripotent stem cells (hPSCs). Distinct from current approaches, we devised a tunable ...

Endocrine therapy is a way of treating conditions such as cancer using hormones. Also known as hormone therapy, it involves adjusting the levels of certain hormones, such as testosterone, estrogen, ...