BIOENGINEER

Novel CNKSR2 Splice Variant Shown to Skip Exon 16 in Boy with Epileptic Encephalopathy

A novel de novo CNKSR2 intronic variant was shown by minigene assays to cause exon 16 skipping, supporting its ...
BIOENGINEER

Base Editing Pinpoints Exon 7 Knockout for High-Yield CHO Antibody Production

Researchers used cytosine base editing to place stop codons in each of six coding exons of the glutamine synthetase gene in ...
ascopubs.org

Identification of Recurrent Insertions and Deletions in Exon 18 and 19 of Human Epidermal Growth Factor Receptor 2 as Potential Drivers in Non–Small-Cell Lung Cancer and ...

Plasma Cell-Free DNA Integrity Assessed by Automated Electrophoresis Predicts the Achievement of Pathologic Complete Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer Patients with ...
The American Journal of Managed Care

Marcia Horn Discusses Advancements in EGFR Exon 20 Insertion+ NSCLC and the Importance of Community

There are promising developments in the pipeline for EGFR exon 20 insertion–positive non–small cell lung cancer (NSCLC), and groups like The Exon 20 Group can help ensure patients are getting access ...
Cancer Network

Sunvozertinib Now Available in US for EGFR Exon 20+ NSCLC

Adults in the US with previously treated locally advanced or metastatic NSCLC harboring EGFR exon 20 insertion mutations can now access sunvozertinib.
Medical Xpress

Poziotinib is active in EGFR exon 20 mutant non-small cell lung cancer

A Phase II clinical trial of poziotinib for non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 mutations, led by researchers at The University of Texas MD Anderson ...
Cancer Network

Zipalertinib May Introduce Another Option to EGFR Exon 20+ NSCLC

Yu, MD, discusses the background of REZILIENT3 and her key takeaways on zipalertinib in EGFR exon 20-mutated NSCLC. This study focused on EGFR exon 20-positive lung cancer, which is a small subset of ...