Stress is known to decrease fertility and sexual behavior, but researchers thought this was because stress hormones lower levels of a brain hormone called gonadotropin releasing hormone, or GnRH.

Reproductive hormones affect all stages of life from gamete production, fertilization, fetal development and parturition, neonatal development and puberty through to adulthood and senescence. The ...

In 1977, the Nobel Prize in Physiology or Medicine was awarded to Roger Guillemin and Andrew Schally for their discovery and synthesis of gonadotropin-releasing hormone (GnRH), a key regulator of ...

Astrocytes in the hypothalamus release prostaglandin E₂ (PGE₂) in response to cell-cell signaling initiated by neurons and glial cells. Upon release, PGE₂ stimulates the secretion of ...

One in 800 children are born with Down syndrome, the most common genetic cause of intellectual disability. The vast majority of cases are caused by having three copies of chromosome 21 instead of two.

Gonadotropin-releasing hormone (GnRH) therapy improves cognitive function in Down syndrome (DS) mouse models and male patients with DS, according to a new study. The findings reveal a previously ...