Previous studies have shown that IL-15 is critical to the induction of T-cell large granular lymphocyte (T-LGL) leukemia. A Phase I trial of a humanized antibody (Hu-Mikβ1) to the IL2/IL15Rβ ...
Hu-Mikβ1 was evaluated in a Phase I clinical trial in patients with T-cell large granular lymphocyte leukemia. Hu-Mikβ1 was shown to be safe in Phase I trials; however, no therapeutic efficacy ...
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