Scientists spent decades uncovering the mechanisms that regulate the human body’s response to oxygen. The implications on the way we understand disease could be significant. This article was produced ...

SALT LAKE CITY— For the first time, a mutation in HIF2α, a specific group of genes known as transcription factors that is involved in red blood cell production and cell metabolism, has been identified ...

The efficacy and adverse event profiles of HIF-PHIs may differ among agents. Although all hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs) target the HIF pathway, the individual ...