By profiling over 16 million immune cells from people aged 22 to 65 after flu vaccination, scientists discovered that memory T cell function changes with age.

BET inhibition in chronic lymphocytic leukemia (CLL) significantly reduces leukemic cell burden and restores T-cell function by modulating the immune microenvironment and reversing T-cell exhaustion.

Once thought to be a flaw in the system, new research suggests that CD4 T cells may actually hold the key to maintaining a ...

Cells have an internal skeleton that maintains their structure and also drives their movement. Known as the cytoskeleton, ...

Therapeutic cancer vaccines have experienced a remarkable resurgence over the past decade, representing a paradigm shift in oncology toward harnessing the immune system's intrinsic ability to combat ...

Scientists hoping to discover better ways to boost immune function — which could lengthen our healthspan and protect immunocompromised patients — may have a new target, according to findings published ...

It must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues.

Researchers have uncovered and then overcome an obstacle that has led to the failure of pioneering efforts in ...