The actress, who stars alongside Demi Moore in the body horror film, says it took "probably a year" for her skin to recover.

Margaret Qualley is proving she’s a Hollywood force in her own right. As if her striking features, raven hair and charming smile weren’t enough to showcase that she was destined for the screen, her acting chops and rapidly growing resume should be.

During a recent appearance on the Happy Sad Confused podcast, Margaret Qualley revealed that the prosthetics she wore in "The Substance" "f--ked up" her skin, saying that it took "a year" for her skin to fully recover from the acne.

"It took me probably, like, a year to recover physically from all of it," she told a podcast about the prosthetics used in the film.

Margaret Qualley says her skin went through a lot while filming 'The Substance.' On Josh Horowitz’s 'Happy Sad Confused' podcast, the actress opened up about the effects of wearing prosthetics for the film and how it impacted her skin.

Jerod Harris/Getty Images Margaret Qualley embraced the acne she was left with after filming The Substance. Qualley, 30, opened up about developing blemishes on her cheeks and chin after having to wear prosthetics while playing Sue in The Substance.

In 'The Substance,' Margaret Qualley wore a mountain of facial prosthetics, which had a detrimental effect on her face.

Margaret Qualley really felt the effects of “The Substance.” The actress, 30, recently appeared on Josh Horowitz’s “Happy Sad Confused” podcast and spoke about how wearing extensive prosthetics to shoot the bloody horror film took a toll on her skin.