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NFL Week 18 Odds, Picks & Predictions

Week 18 NFL odds, lines, best bets, predictions: Computer model backing Packers and Titans

All of the updated Week 18 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 18 NFL picks now.

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NFL picks, predictions, odds for Week 18: It’s the final coutdown

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Lions at Bears: Predictions, picks and odds for NFL Week 18 game

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Best NFL Bets for Week 18: Our Experts’ Favorite NFL Picks Against the Spread

The final week of the NFL regular season is always tricky when it comes to setting the spreads.

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NFL playoff scenarios for divisions, berths, top seeds, seeding in AFC, NFC

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NFL Player Prop Picks: Week 18 Best Bets

2025 NFL MVP Odds, Race: Drake Maye Takes Over as Favorite in 2-Man Contest

Matthew Stafford is no longer holding steady as the favorite for NFL MVP. Let's take a look at the latest at DraftKings Sportsbook as of Dec. 30, as well as what to know about the contenders.

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NFL MVP odds: Drake Maye favored over Matthew Stafford entering Week 18

Matthew Stafford was the odds-on favorite to win the NFL MVP award entering Week 17. Drake Maye will lead the NFL MVP odds heading to Week 18.

Tennessee Titans vs. Jacksonville Jaguars: NFL experts' Week 18 picks

NFL experts from around the league make their picks in the Tennessee Titans and Jacksonville Jaguars Week 18 matchup.

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Titans vs. Jaguars (Jan 4, 2026) Pregame - ESPN

Pregame analysis and predictions of the Tennessee Titans vs. Jacksonville Jaguars NFL game to be played on January 4, 2026 on ESPN.