The PIK3CA gene, which encodes the p110α subunit of phosphoinositide 3-kinase (PI3K), is among the most frequently mutated oncogenes in cancer. These mutations drive tumor progression, metabolic ...
The PIK3CA gene, which encodes the p110α subunit of phosphoinositide 3-kinase (PI3K), is among the most frequently mutated oncogenes in cancer. These mutations drive tumor progression ...
The review highlights next-generation therapies that specifically target PIK3CA mutations with improved selectivity and reduced toxicity. Several promising inhibitors, including RLY-2608, STX-478 ...
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