New data unexpectedly suggest that sera from patients with PR3-ANCA-associated vasculitis are less reactive than those of healthy controls to the 'antisense' product of the PR3 gene. How does this ...

Please provide your email address to receive an email when new articles are posted on . DESTIN, Fla. — Practical, individualized care for patients with antineutrophil cytoplasmic antibody-associated ...

Vasculitis is a group of conditions that results in inflammation of the blood vessels. Symptoms include rash, shortness of breath, vision loss, and kidney failure depending on the location of the ...

Please provide your email address to receive an email when new articles are posted on . Rheumatologists should assess for PR3- and MPO-ANCA using a “high-quality antigen-specific assay” as the primary ...

Biopsy testing confirmed 2 distinct, simultaneous primary glomerular diseases rather than AAV-driven secondary FSGS. A rare case of simultaneous primary focal segmental glomerulosclerosis (FSGS) and ...

In patients with ANCA-associated vasculitis (AAV), double seropositivity for MPO-ANCA and PR3-ANCA is linked to worse remission rates compared with either AAV type alone. Idiopathic ANCA-associated ...

Patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) who presented with antimyeloperoxidase (anti-MPO) ANCA appeared to have a higher risk for major adverse ...

New research provides insights into the involvement of leukocyte proteinase 3 (PR3, also known as myeloblastin), and of anti-neutrophil cytoplasmic antibodies directed against this serine protease ...

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, demonstrated an association between age of diagnosis and clinical characteristics and ...

Mycophenolate mofetil (CellCept) was as effective as cyclophosphamide for remission induction in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis, Japanese researchers reported. In a ...