Bacillus anthracis, the causative agent of anthrax, possesses a uniquely complex cell envelope that is critical to its pathogenicity. Central to its virulence are the secondary cell wall ...

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the ...

Anthrax is an infectious disease caused by the bacterium Bacillus anthracis. While the infection is often treatable in its early stages, once the disease has progressed beyond the “point of no return” ...

In the 2001 “Amerithrax” attacks, anthrax-causing spores were sent through the mail to media outlets and members of Congress, sickening at least 22 people and killing five. Antibiotic-resistant ...

In October 2001, letters containing virulent anthrax bacteria were sent through the U.S. mail. Between October 4 and November 20, 2001, 22 individuals developed anthrax and 5 of these cases were fatal ...

Researchers show that a cocktail of growth factors reversed would-be lethal cell damage in mice with anthrax, suggesting that this approach could be adapted for use in patients. Anthrax, an infectious ...

With the emergence of multi-drug resistant (MDR) “super bugs” the need for new bactericidal approaches is growing in urgency. Compounding the threat of MDR, is the rise of antibiotic resistance in ...

Anthrax, an infectious disease caused by the bacterium Bacillus anthracis, is often treatable in its early stages. But once the disease has progressed beyond the "point of no return" after just a few ...