Just as robust stone walls and expansive moat waters protect a castle and its inhabitants from foreign intruders, the body’s adaptive immunity mounts two defensive arms against pathogens: B cells and ...

The articles in this focus issue discuss progress towards a more complete understanding of memory in the innate immune system, and efforts to exploit "trained immunity" for the development of new ...

A new review by Dr. Ruyuan Wang and an international team of researchers explores the complex interactions between the innate and adaptive immune systems, shedding light on regulatory mechanisms in ...

New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. Germinal centers are high-speed evolution ...

The immune-boosting power of a fever is surprisingly ancient. Cold-blooded creatures like fish typically move to warmer environments to help fight infections. In one fish species, Nile tilapia, that ...

Wesley Freppel does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

A recent study published in the journal Immunology analyzed whether sex mattered in the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 pandemic has ...

Hypertension is one of the most prevalent non-transmittable diseases in the world, with 29% of the world's population expected to suffer from the condition by 2025. Despite substantial advances in ...

Smoking tobacco is so harmful to the body that it changes a person’s immune system, leaving them vulnerable to more disease and infection even years after they’ve quit, a new study found. Although ...

Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted ...