Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...
Fifteen years ago, physicists worked out a method to increase image contrast by hitting the electron imaging beam with an ...
A new microscope method reveals details that were difficult to see before, helping researchers study proteins, cells, and ...
Biohub and UC Berkeley show that the laser phase plate, a revolutionary device with a laser 100 million times brighter than ...
In a landmark achievement in biological imaging, researchers at the University of California, Berkeley and Biohub today ...
Installed in a custom Titan Krios, the laser phase plate enhances motion correction, early‑frame recovery, and 3D classification and alignment.
Quantitative phase microscopies (QPMs) play a pivotal role in bio-imaging, offering unique insights that complement fluorescence imaging. They provide essential data on mass distribution and transport ...
The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...
Typically in optical microscopy, the signal-to-noise ratio (SNR) is calculated to quantify the image contrast which indicates how well different regions of interest in the image can be differentiated.
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