CRISPR-Cas systems are widely used in genome engineering applications. They contain RNA-guided ribonucleoprotein (RNP) complexes that selectively modify DNA sequences at any specific location in the ...

High quality samples are key for data reproducibility and reliability. For biophysical protein characterization, quality samples are defined as those containing pure, soluble protein exhibiting ...

Mass Photometry (MP) and Macro Mass Photometry (MMP) are complementary, label-free techniques that analyze biomolecules and therapeutic vectors directly in solution with single-particle resolution.

In this way, the mass photometer was able to distinguish between the two types of molecules in a way that was quicker and just as accurate as conventional methods." Given that the full-to-empty ...

Mass photometry is able to offer users efficient and accurate characterization of complex samples, including those that feature membrane mimetics. This technique is ideal for streamlining membrane ...

Approximately 25 percent of proteins localize to membranes, where they act as receptors and signaling molecules in biological processes, including respiration, neurotransmission, and molecular ...

Refeyn, the company behind pioneering mass photometry technologies, has taken another step to assure mass photometry is a simpler, more efficient bioanalytics tool with the release of a powerful ...

Aggregation is an important quality attribute of many protein-based biopharmaceuticals, including monoclonal antibodies (mAbs), that can influence product efficacy and safety; as such monitoring of ...

MR. WALSH'S book may be regarded as a useful supplement to pre-War works on illumination. The text may be conveniently divided into four main sections. We have first an account of the effect of light ...

ABSTRACT We have obtained the first time‐resolved photometry of the double degenerate white dwarf/white dwarf binary star WD 0957−666. Light curves of the binary are essentially indistinguishable from ...

The US Pharmacopeia (USP) has recognized mass photometry as a key orthogonal method for characterizing its new adeno-associated virus (AAV) reference standards, as referenced in the draft general ...