Located at the cellular interface, membrane proteins play critical regulatory roles in the signaling between a cell and its interacting environment, making them popular and ideal drug targets.

Researchers have created a deep learning pipeline for designing soluble analogues of key protein structures used in pharmaceutical development, sidestepping the prohibitive cost of extracting these ...

Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their ...

Membrane proteins are ubiquitous cellular components that are responsible for a wide array of cellular and molecular activities, including drug metabolism, lipid shuttling, and antibiotic resistance.

Cellular membrane proteins play important roles in cellular transport, signaling, and cell-to-cell communication. Malfunction in membrane proteins can lead to serious diseases, such as cancer. However ...

Discover how mapping plasma proteins to diseases in 53,000 adults is transforming diagnostics, advancing treatments, and paving the way for personalized healthcare solutions. Study: Atlas of the ...

Protein aggregation is typical of various neurodegenerative diseases such as Alzheimer's, Parkinson's and prion diseases such as Creutzfeld-Jakob disease. A research team has now used new in vitro and ...

Scientists at UT Southwestern in Dallas say they have finally nailed down the human protein that makes cells literally burst ...

Ikoma, Japan—Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria. Their formidable defensive ...

Study data indicate that membrane perforation registers as danger and is sufficient to launch type 2 immune pathways in the airway epithelium. The authors argue that many otherwise unrelated allergens ...