Mapping Interactions of Alzheimer’s-related Tau Protein Reveals Pathway for New Potential Treatments
The dementia associated Tau protein — known for its role in microtubule regulation — has now been found to also play important roles in the nerve signaling and mitochondrial function in the brain. A ...
An international research team headed by scientists from Nanyang Technological University, Singapore and the Center for ...
Shares of Princeton-based Cytogen (Nasdaq: CYTO) rose 27.06% today after the company said scientists at its AxCell Biosciences unit have mapped all interactions of the known proteins found in one of ...
Ahmet Coskun's lab has developed iseqPLA to map protein interactions. An artistic rendering of sub-cellular activity: The cell membrane is seen at the top, nucleus on the bottom/right. Protein pairs ...
The decline of brain endothelial cell (BEC) function, due to aging, is a contributor to neurological disease. BECs lining the inner walls of blood vessels regulate the exchange of molecules across the ...
Researchers at LMU and the SyNergy Cluster of Excellence have analyzed how the proteome of specific brain cells changes as we age. For the neurons in the brain to work smoothly and be able to process ...
Bioengineers at the University of California San Diego have developed a powerful new technology that can map the entire network of RNA-protein interactions inside human cells — an achievement that ...
Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...
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Spatial proteomics: Mapping protein organization across cells and tissues
Advancements in spatial proteomics enable detailed tissue mapping, linking protein localization to disease mechanisms and ...
Peptide mapping is an essential step in characterizing, identifying, and monitoring a wide range of properties of target proteins in biotherapeutic studies. Peptide mapping for biotherapeutic proteins ...
For the neurons in the brain to work smoothly and be able to process information, the central nervous system needs a strictly regulated environment. This is maintained by the blood-brain barrier, ...
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