Business Wire

Paracrine Announces Publication of STAR Trial, Including Improvement in Hand Function and Quality of Life in Patients With Diffuse Cutaneous Scleroderma

SAN DIEGO--(BUSINESS WIRE)--Paracrine, Inc., announced today the online publication (ahead of print) of the findings from the STAR I trial in Arthritis & Rheumatology Journal, the official journal of ...
Nature

Scleroderma: oral, maxillofacial and radiographic manifestations for dental practitioners

Scleroderma is an autoimmune condition of unknown aetiology with a range of manifestations, which can be limited to the skin or can extend to be multisystemic. It is characterised by fibrosis, ...
Labroots

Scientists Find a Biomarker for Better Scleroderma Detection

Scleroderma, or systemic sclerosis refers to a disorder in which the skin and connective tissues of the body start to thicken and harden because of the overproduction of a protein called collagen.
Business Wire

Paracrine Receives FDA Approval to Launch a U.S. Pivotal Trial in Patients With Hand Dysfunction Due to Diffuse Cutaneous Scleroderma

Pivotal trial to support marketing approval of regenerative cells processed with the Celution® System to commence in Q2 2022 SAN DIEGO--(BUSINESS WIRE)--Paracrine, Inc. announced today that the FDA ...
Medical Xpress

Blood biomarker could help identify patients at risk for severe scleroderma

Systemic sclerosis, or scleroderma, causes the hardening of skin and connective tissues. Often, the disease harms other organs, such as the heart, kidneys, lungs, and gastrointestinal tract, and it ...
Nature

State-of-the-art evidence in the treatment of systemic sclerosis

Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease with multi-organ involvement, fibrosis and vasculopathy. Treatment in SSc, including early diffuse cutaneous SSc (dcSSc) and the ...
The American Journal of Managed Care

Systemic Sclerosis With Associated Interstitial Lung Disease: Management Considerations and Future Directions

Systemic sclerosis (SSc), also referred to as scleroderma, is a rare autoimmune disease associated with vasculopathy, inflammation, and fibrosis of the skin and/or internal organs. Interstitial lung ...
Medscape

Serum Type I Interferon Score May Predict Outcome in Diffuse Cutaneous Systemic Sclerosis

High serum type I interferon (IFN) scores, measured through six chemokines, correlated with poorer lung function and health-related quality of life in patients with diffuse cutaneous systemic ...
Healio

ILD frequency, cardiac symptoms distinguish diffuse, limited juvenile scleroderma subtypes

Please provide your email address to receive an email when new articles are posted on . The classically defined diffuse subtype of juvenile systemic sclerosis demonstrates more globally severe disease ...
National Academies of Sciences%2c Engineering%2c and Medicine

Selected Immune Disorders and Disability

Systemic sclerosis (SSc), or scleroderma, is a chronic, multisystem autoimmune rheumatic disease characterized by exaggerated fibrosis, vasculopathy, and derangements of the immune system. When ...
Medscape

Early Success Seen With CAR T-Cell Therapy for Systemic Sclerosis

CD19-targeting chimeric antigen receptor (CAR) T-cell therapy shows potential to intercept fibrotic organ manifestations and improve disease measures in patients with diffuse cutaneous systemic ...