NY resident Sebastien Beauzile was treated with a pioneering new gene therapy approach called Lyfgenia, curing his sickle ...

A recent Vanderbilt study has found a cure for sickle cell disease, a blood disorder where the body creates mutated red blood ...

Sickle-cell disease, usually presenting in childhood ... that can lead to death and severe complications. Not all inherited variants of haemoglobin are detrimental, a concept known as genetic ...

Feb. 25, 2025 — A bone marrow transplant process is safe and curative for adults with sickle cell disease, according to results of a trial completed at about 20 cancer ... Brains of People With ...

Esther Nkemakolam runs her fingers through kinetic sand and sings a “Moana” song as UPMC Children’s Hospital nurse Taylor Brennan gets to work drawing blood. Esther is back for her monthly blood ...

A recent review published in the journal Engineering delves into the significant advancements and potential of CRISPR ...

Crizanlizumab (Adakveo) failed to outperform placebo in patients with sickle cell disease, the phase III STAND trial showed.

Medically reviewed by Steffini Stalos, DO People with sickle cell disease are immunocompromised, which means they have an increased risk of infection. For this reason, immunizations are an important ...

By driving highly protective variants to high prevalence ... is demonstrated by positive selection for traits such as sickle-cell hemoglobin (Sabeti et al., 2006). Natural human defenses have ...

If we look at the registry overall — looking at all types of sickle cell disease severities and genotypes — the overall rate of use is about 21%, which is very low. If we dig deeper and look ...

Sickle cell anemia, first described in 1910, primarily affects people of African, Mediterranean and Middle Eastern descent.