It can affect internal organs and other body systems as it progresses, but this happens less frequently than with other forms of systemic scleroderma. Skin changes are an early ... like disorders ...

Thus, topical approaches may offer effective, localized, well-tolerated alternatives to the systemic regimen. However, their value in the management of uncomplicated skin infections is not yet ...

Cutaneous fungal infections that generally require systemic antifungal therapy include tinea capitis and onychomycosis. Tinea capitis, which is most often caused by Trichophyton tonsurans ...

Most of the systemic fungal infections, like histoplasmosis ... loss of appetite, skin masses and sores, changes to temperament, seizures, and circling. They can develop symptoms associated ...

IL-23, or IL-17 reduced serious infections, while tofacitinib increased infection risk, according to one study.

Lawrence F. Eichenfield, MD, FAAD, from Rady Children's Hospital and UC San Diego School of Medicine, highlighted the effectiveness of ruxolitinib cream as a nonsteroidal topical treatment for atopic ...