Early results reveal how a single‑cell spatial platform maps stromal barriers that limit antibody delivery and target engagement in human solid tumors.

Spatial proteomics is a spatial biology method that helps study the spatial distribution of the proteins within cells and tissues. The subcellular localization of proteins is intrinsic to cellular ...

In a recent study published in the journal Nature, researchers developed spatial aging clocks using single-cell transcriptomics to explore cell-type-specific interactions and their impact on brain ...

Capturing spatial information is essential to elucidate how cells function and interact within their native tissue environment. However, the initial spatial transcriptomics techniques have several ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...

Chang leads assay and applications development at Takara Bio, driving the commercialization of novel spatial genomics products. She has extensive experience in single-cell multiomics technologies and ...

Up to half of patients with Crohn's disease, an inflammatory bowel disease, develop a complication called fibrosis, where the gut becomes scarred and obstructed, causing pain and bloating. Currently, ...

A new computational method could dramatically accelerate efforts to map the body's cells in space, according to a study published in Nature Genetics. Spatial multi-omics technologies—often described ...

MSK immunologist Dr. Andrea Schietinger and colleagues found that a 'triad' of immune cells is required to kill cancer cells. The discovery could alter the way doctors administer immunotherapies.

Heat and drought stress are major environmental factors that severely limit crop growth, productivity, and global food security. As climate change ...