Spike glycoprotein of SARS-CoV-2 variants plays a critical role in infection and transmission through its interaction with human angiotensin converting enzyme 2 (hACE2) receptors. Prior findings using ...

New computer models and simulations from Los Alamos National Laboratory are showing researchers how the virus that causes COVID-19 manages to use its spike protein to fuse with and infect human cells.

Researchers created atomic-level models of the spike protein that plays a key role in COVID-19 infection and immunity, revealing how the protein bends and moves as it seeks to engage receptors. When ...

CHAMPAIGN, Ill. — When the coronavirus causing COVID-19 infects human cells, the cell’s protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, ...