To gain insight into why antibody responses to malarial antigens tend to be short lived, we studied antigen-specific memory B cells from donors in an area where malaria is endemic. We compared ...

Screening of a Plasmodium falciparum genomic expression library for antigens expressed at the pre-erythrocytic stages resulted in the isolation of a recombinant phage (DG249) whose insert corresponded ...

Malaria vaccine shows over 50% efficacy in adults following controlled human malaria infection, supporting further trials in children.

Plasmodium falciparum is responsible for the most virulent form of human malaria. This protozoan parasite spends part of its lifecycle inside the red blood cells (RBCs) of its host. The mature human ...

Mali: A phase 2 randomized controlled trial published in The Lancet Infectious Diseases has revealed that a multistage malaria vaccine provided encouraging protection against controlled human malaria ...

Currently, few antimalarial treatments exist that effectively kill liver-stage malaria parasite Plasmodium vivax, which can lay dormant for months or even years. Researchers have reported a new drug ...

DURHAM, N.C. -- When the malaria-causing Plasmodium parasite first slips into the human bloodstream, injected by the bite of an infected mosquito, it does not immediately target red blood cells.

NEW YORK (Reuters Health) - A panel of antibodies can accurately detect recent liver-stage Plasmodium vivax infection, researchers report. Current diagnostics cannot detect clinically silent ...

Researchers have discovered a group of chemical compounds that might one day be developed into drugs that can treat malaria infection in both the liver and the bloodstream. Researchers have discovered ...

Researchers have developed a new antimalarial drug candidate designed to address the growing challenge of drug resistance and ...

Australian researchers have worked with global phamarceutical company MSD to co-develop a new antimalarial drug candidate ...