UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...
Universal gene‑edited CAR‑T therapies turn donor T cells into off‑the‑shelf cancer treatments, cutting delays and costs while ...
How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy ...
Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.
Although rheumatologists consider chimeric antigen receptor T-cell therapy “potentially transformative,” nearly 70% remain ...
A new multi-pronged antibody design could help immune cells receive stronger activation signals against cancer. Researchers ...
Researchers have found a reliable way to grow helper T cells from stem cells, solving a major challenge in immune-based ...
Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...
Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...
In a phase 1 study, anti-CD7 chimeric antigen receptor (CAR) T cells induced complete remission in children and adults with relapsed or refractory T-cell acute lymphoblastic leukemia (ALL), with 82% ...
While presenting this year’s Nobel Prize in Physiology or Medicine to three immunologists who discovered and characterized regulatory T cells, committee chair Olle Kämpe, M.D., Ph.D., told the ...