A new paper from MUSC Hollings Cancer Center researchers is helping to reveal the "rules" for engineering chimeric antigen receptor (CAR) Tregs. Tregs, or T-regulatory cells, have shown promise in ...

A new study by Cambridge University scientists revealed promising information about regulatory T cells, a type of white blood cells that combat autoimmune and inflammatory diseases in the body.

Follicular regulatory T (Tfr) cells modulate germinal center T and B cell responses, but how Tfr may control allograft rejection is still unclear. Here the authors show, using mouse kidney ...

T cells, which are the frontline warriors in the battle against infections, have been a major focus of research. Regulatory T cells (Tregs) are specialized immune cells that have a challenging ...

Psoriasis is one of the most common chronic inflammatory skin diseases, affecting around 250,000 people in Austria.

Lupus is an autoimmune disease where the body’s immune system attacks its own tissues and organs, causing inflammation and damaging organs.

Researchers have harnessed synthetic biology to engineer chimeric antigen receptor (CAR) T cells that precisely target and destroy cancer. However, these powerful cells can also attack healthy tissues ...

This study reports valuable findings on the role of Layilin in the motility and suppressive capacity of clonal expanded regulatory T cells (Tregs) in the skin. Although the strength of the study is ...

Immunostimulant therapy using agonistic cytokines or activating antibodies has been associated with off-target side effects, failure to preferentially activate cytotoxic lymphocytes (CTLs) over ...