A new multi-pronged antibody design could help immune cells receive stronger activation signals against cancer. Researchers ...

How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy ...

Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

Researchers have developed a new class of antibodies that amplify the immune system’s ability to fight cancer. By clustering ...

A new study in Nature Communications reveals how immune cells rapidly shut down their response after activation, preventing ...

A research team led by Professor Chen Peng from the College of Chemistry and Molecular Engineering at Peking University has ...

The orchestration of T cell activation is central to immune defence and self-tolerance. Recent advances have revealed that T cells integrate signals from their antigen receptors alongside a network of ...

A new AI tool that models how variations in peptides change T cell receptor binding could help design immunotherapies with fewer off-target effects. Protein complexes that adorn the surface of T cells ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...