Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an ...

Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.

How do immune cells strike a balance, unleashing rapid attacks against pathogens or cancer, while avoiding damage to healthy ...

Trojan horse” approach may enable ‘antigen-independent’ therapy with potential to treat cancers not traditionally amenable to immunotherapy.

A new multi-pronged antibody design could help immune cells receive stronger activation signals against cancer. Researchers ...

Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, ...

Researchers have developed a new class of antibodies that amplify the immune system’s ability to fight cancer. By clustering ...

Kennedy researchers have uncovered key design parameters for bispecific T-cell engagers (TcEs)—a class of cancer immunotherapy drugs. The findings may help unlock the full potential of TcEs and ...

CAR T therapy has been transformative in the battle against deadly cancers. Scientists extract a patient’s own immune cells, genetically engineer them to target a specific type of cancer, and infuse ...

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be ...