The wingless type MMTV integration (Wnt) activated intracellular signaling cascade regulates multiple biological processes, ranging from embryogenesis and organogenesis to adult homeostasis. The Wnt ...
Tumor necrosis factor (TNF) signaling determines the cell’s fate by promoting either survival or cell death via apoptosis, necroptosis or pyroptosis. Excessive or chronic cell death by TNF was shown ...
This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the ...
This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the ...
Shi’s study, "Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling," was recently published in Nature Communications. “Concerted efforts ...
While agents like AbbVie's Humira have transformed the treatment landscape, not all patients benefit equally from the drug.