In 2015, Bluestone led a small clinical trial to isolate and grow Tregs from diabetes patients and then reinfuse the cells ...
Every day, your immune system performs a delicate balancing act, attacking harmful invaders while protecting your own tissues ...
HOUSTON--(BUSINESS WIRE)--Coya Therapeutics, Inc. (NASDAQ: COYA) (“Coya” or the “Company”), a clinical-stage biotechnology company developing biologics intended to enhance regulatory T cell (Treg) ...
The prize honored discoveries that defined peripheral immune tolerance through regulatory T cells (Tregs) and the FOXP3 gene, ...
Shimon Sakaguchi discovered T-reg immune cells. Mary Brunkow and Fred Ramsdell identified the cells’ role in autoimmune disease.
A new research paper was published in Volume 16 of Oncotarget on July 9, 2025, titled "A novel anti-human CD25 mAb with preferential reactivity to activated T regulatory cells depletes them from the ...
Mitochondrial dysfunction triggered by ER stress was found to make Tregs unstable and to cause them to lose their protective ...
During infections, the immune system needs to distinguish foreign antigens that are expressed by invading bacteria and viruses from self-antigens that are expressed by cells of the body. If not, the ...
This story has been updated. The human immune system is our body’s primary line of defense against harmful microbes, viruses and other invaders—but that defense line can sometimes run amok and attack ...
Study met Primary and Secondary Endpoints for Safety and Regulatory T cell (Treg) Cell Population Enhancement, respectively, with no off-target effects on T effector lymphocytes, providing further ...