ALZFORUM13d
From the Meninges, Regulatory T Cells Keep Brain Inflammation in Check
Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...
Nature17y
Regulatory T-cell development: is Foxp3 the decider?
Foxp3 may steer T cells down specific pathways by amplifying and stabilizing features advantageous to Treg differentiation, such as CD25 and CTLA-4 expression, or by repressing features ...
Nature12y
IL-22 deficiency in donor T cells attenuates murine acute graft-versus-host disease mortality while sparing the graft-versus-leukemia effect
Treg cell analysis was performed by cell surface staining with FITC-CD3, Pacific Blue-CD4 (from Biolegend) and APC-CD25 (from BD Biosciences), cells were then fixed and permeabilized with Foxp3 ...