Researchers have identified a key role microglia play in melanoma brain metastases progression and mechanisms to target them.

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic ...

Researchers studied the gene expression of lymphatic endothelial cells in melanoma (a type of skin cancer) and healthy mouse ...

When a tumor develops, it creates a structure around itself called the tumor stroma, within which blood and lymphatic vessels ...

Basal cell carcinomas, the most common form of skin cancer, occur in chronically sun-exposed areas such as the face. Locally advanced tumors in particular can be difficult to treat surgically.

Lung endothelial cells in the tumor microenvironment produced more CXCL12, a compound that attracts plasma cells. In addition, immune T cells, typically in charge of fighting the tumor, were excluded ...

Many cells comprise the tumor microenvironment, but endothelial cells are particularly crucial. They line blood vessels, regulating blood flow and inflammation, and their cell junctions are the ...