Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, ...

Further acknowledgement and study of the tumor microenvironment in diffuse large B-cell lymphoma (DLBCL) could eventually result in much more personalized—and effective—treatments. DLBCL being ...

Researchers have identified C5aR1 as a novel biomarker for metastasis risk and poor prognosis in patients with cutaneous squamous cell carcinoma (cSCC), the most common type of metastatic skin cancer.

This article explores how researchers are using spatially resolved methods to explore diverse biological processes from ...

Figure 1: Skin carcinogenesis in wild-type and TNF-α –/– mice. TNF-α is a pleiotropic cytokine that could influence cells in both the epidermis and dermis, and early and late stages of tumor ...

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body’s immune response critical for their elimination. Researchers at Baylor College of Medicine and ...

Pancreatic cancer cells are known for being hard to treat, partly because they change the environment around them to block drugs and immune cells. Scientists discovered that these tumors use a ...

The tumor microenvironment is a battleground where infiltrating immune cells either subdue or promote a cancer, all while cancer cells try to dampen the body’s defenses. 1,2 Scientists have studied ...

Glucose is the fuel to the cellular engine. It powers the cell’s functions and serves as the raw material for synthesizing various essential biomolecules, including the sugar backbone of DNA and RNA.

Researchers at Baylor College of Medicine, Texas Children’s Hospital, the Hospital for Sick Children in Toronto and collaborating institutions reveal in Nature Cell Biology a strategy that helps ...

The stroma to tumor ratio potentially identifies higher risk bladder cancer tumors and might help guide immunotherapy. Bladder tumors with higher stromal content may have a more immunosuppressive ...