The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and ...

The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...

Researchers are edging closer to something long imagined but never quite within reach: a single vaccine platform that could ...

A redesigned immune-activating cancer drug has produced striking early results in a small clinical trial, shrinking tumors ...

Further acknowledgement and study of the tumor microenvironment in diffuse large B-cell lymphoma (DLBCL) could eventually result in much more personalized—and effective—treatments. DLBCL being ...

A new drug strategy that regulates the tumor immune microenvironment may transform a tumor that resists immunotherapy into a susceptible one, according to a new study. A new drug strategy that ...

Researchers have identified C5aR1 as a novel biomarker for metastasis risk and poor prognosis in patients with cutaneous squamous cell carcinoma (cSCC), the most common type of metastatic skin cancer.

The tumor microenvironment is a battleground where infiltrating immune cells either subdue or promote a cancer, all while cancer cells try to dampen the body’s defenses. 1,2 Scientists have studied ...

A study published in Science Advances reveals a novel strategy that allows tumors to evade the body’s immune response critical for their elimination. Researchers at Baylor College of Medicine and ...

Figure 1: Skin carcinogenesis in wild-type and TNF-α –/– mice. TNF-α is a pleiotropic cytokine that could influence cells in both the epidermis and dermis, and early and late stages of tumor ...

The stroma to tumor ratio potentially identifies higher risk bladder cancer tumors and might help guide immunotherapy. Bladder tumors with higher stromal content may have a more immunosuppressive ...