Immune cells work to fight infection and other diseases. Different subsets work together to elicit a healthy immune response; ...
The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and ...
The integration of PD-1 inhibitors into standard chemotherapy and radiotherapy regimens has revolutionized nasopharyngeal ...
The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...
Figure 1: Skin carcinogenesis in wild-type and TNF-α –/– mice. TNF-α is a pleiotropic cytokine that could influence cells in both the epidermis and dermis, and early and late stages of tumor ...
A study published in Science Advances reveals a novel strategy that allows tumors to evade the body’s immune response critical for their elimination. Researchers at Baylor College of Medicine and ...
"Using 2 complementary methods, we demonstrated that T cells in the lung tumor microenvironment do, in fact, demonstrate evidence of poor immune function." — Brinda Emu, MD, Yale University School of ...
The tumor microenvironment is a battleground where infiltrating immune cells either subdue or promote a cancer, all while cancer cells try to dampen the body’s defenses. 1,2 Scientists have studied ...
The stroma to tumor ratio potentially identifies higher risk bladder cancer tumors and might help guide immunotherapy. Bladder tumors with higher stromal content may have a more immunosuppressive ...
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