Real world treatment practices and outcomes of metastatic Merkel cell carcinoma: A retrospective study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract does not ...
The tumor microenvironment (TME) consists of mediators surrounding a tumor, including diverse cell types, blood vessels, and other cellular components. Certain elements of the TME can benefit patients ...
Johns Hopkins University cancer researcher Mikala Egeblad has received the 2025 Ernst W. Bertner Memorial Award in recognition of her research into how tumor microenvironments impact cancer ...
Neoadjuvant pembrolizumab (3 doses) in stage I–III disease yielded a 71% pCR rate and only one melanoma-specific survival event at 3 years post-resection. Experts discuss the SWOG S1512 trial of ...
The inflammatory tumor microenvironment (TME) is a complex network of cancer, immune, and stromal cells interacting through cytokines and growth factors to drive tumor growth, angiogenesis, and immune ...
The tissue adjacent to a tumor behaves differently than areas farther away: The tumor’s cancerous cells influence their surroundings, blocking the body’s immune defenses and creating a sort of haven ...
A phase II trial found that T-VEC improved tumor resectability in 50% of patients, leading to early study discontinuation, with strong immune response activation and minimal side effects. Study: ...
"Using 2 complementary methods, we demonstrated that T cells in the lung tumor microenvironment do, in fact, demonstrate evidence of poor immune function." — Brinda Emu, MD, Yale University School of ...
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