T-cell engagers are antibody-based therapeutics that can reprogram T cells for antigen-specific elimination of target cells. The modality has remained a big draw for Big Pharma, with Eli Lilly penning ...

Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an ...

Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...

Cancer immunotherapy is a type of cancer treatment that harnesses the immune system to fight cancer cells. The treatment ...

Trojan horse” approach may enable ‘antigen-independent’ therapy with potential to treat cancers not traditionally amenable to immunotherapy.

Universal gene‑edited CAR‑T therapies turn donor T cells into off‑the‑shelf cancer treatments, cutting delays and costs while ...

Early evidence suggests safety, efficacy, while awaiting data on durability in broader pop ...

Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, ...

Researchers found an antibody that seems to play a role in people with better lung cancer prognoses, but turning it into a ...