Although rheumatologists consider chimeric antigen receptor T-cell therapy “potentially transformative,” nearly 70% remain ...

The Nobel Prize in Medicine was awarded on Monday to three scientists for discovering how a particular kind of cell can stop the body's immune system from attacking itself. The discovery of these ...

The FDA's breakthrough therapy designation facilitates accelerated development and regulatory review for therapies showing ...

UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes ...

CAR-T is a powerful tool which is still evolving. Here we highlight what is new in CAR-T cell therapy Cancer cells often play hide-and-seek with the immune system in an attempt to evade catastrophic ...

Every time our body encounters a new disease-causing agent, a crucial defense system called adaptive immunity comes into play ...

Editing CAR T cells to produce inflammatory cytokines helps them enter solid tumors and promote cancer killing.

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...

Patients treated in an outpatient setting who later required admission spent an average of 12.1 days in the hospital, ...

Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...