A team of scientists has zeroed in on an enzyme that could revolutionize Lyme disease treatment. By uncovering the crucial ...

Lyme disease’s Achilles’ Heel has been discovered.By uncovering the crucial role of BbLDH in bacterial survival and ...

Researchers have identified BbLDH as a critical component for the survival and infectivity of Borrelia burgdorferi, the bacteria responsible for Lyme disease. The fundamental nature of BbLDH lies in ...

burgdorferi does not use thiamin as a cofactor and instead relies on lactate dehydrogenase (BbLDH) to convert pyruvate to lactate to balance the NADH/NAD + ratio, which has not been reported in any ...

Once they confirmed that the enzyme was, indeed a good target, they found several molecular candidates that could effectively shut BbLDH down. “We discovered that BbLDH has a unique biochemical and ...

Researchers at Virginia Commonwealth University discovered an enzyme, lactate dehydrogenase , as a potential therapeutic ...

Lyme disease, spread by infected ticks, starts with flu-like symptoms but can lead to serious neurological, heart, and joint ...

burgdorferi does not use thiamin as a cofactor and instead relies on lactate dehydrogenase (BbLDH) to convert pyruvate to lactate to balance the NADH/NAD+ ratio, which has not been reported in any ...

Researchers have discovered that an enzyme can serve as an ideal target for developing new therapeutics against Lyme disease, and ...

The Role of BbLDH in Borrelia burgdorferi Lyme disease, the most reported tick-borne illness in the United States and Europe, is primarily caused by the bacterium B. burgdorferi. One of the intriguing ...

burgdorferi does not use thiamin as a cofactor and instead relies on lactate dehydrogenase (BbLDH) to convert pyruvate to lactate to balance the NADH/NAD + ratio, which has not been reported in ...