An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

UC San Diego researchers uncover enzyme behind cancer genome chaos, pointing to potential therapies for aggressive tumors.

A noninvasive blood test to detect genetic material shed by tumors may help clinicians identify adverse events related to ...

To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells.

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

A cutting-edge therapy using base-edited immune cells is offering a major breakthrough for patients with one of the toughest ...

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

A cutting-edge base-edited CAR T-cell therapy is opening a revolutionary new frontier for patients battling aggressive T-cell ...