In many experimental situations, a response surface design is divided into several blocks to control an extraneous source of variation. The traditional approach in most response surface applications ...

D. R. Cox, Randomization in the Design of Experiments, International Statistical Review / Revue Internationale de Statistique, Vol. 77, No. 3 (December 2009), pp. 415-429 ...

The order of treatments was randomized using randomization block design, which was generated with a random generator script in SAS version 9.2. Participants were blinded to the treatment.

Randomization was based on a permuted-block design (with random block sizes of 2, 4, or 6), was stratified according to center and symptomatic status, and was performed after the patient, surgeon ...