Family runs deep in the NFL, and two San Francisco 49ers captains showed that their support extends beyond team colors.

The 49ers A.P.E.X. Employee Resource Group came together to create an apparel line that pays homage to the roots of AAPI ...

The Detroit Lions and San Francisco 49ers play Monday, Dec. 30, at the 49ers' Levi's Stadium in a game on the NFL Week 17 schedule. Which team will win the Monday Night Football game? Check out ...

George Kittle didn't have a catch. All three players, though, made big plays in the second half as the San Francisco 49ers rallied from 17 points down to beat the Detroit Lions and advance to the ...

The last time the Detroit Lions played at Levi’s Stadium, they endured a heartbreaking 34-31 loss to the San Francisco 49ers in the NFC title game last season. When the teams meet again next ...

And yet you guys managed to bring thoughtfulness — and even some mirth — to this week’s San Francisco 49ers holiday mailbag. Well done! I hope your stockings were full of frankincense and myrrh.

Bo Nix and the Denver Broncos are in the thick of the AFC wild-card race, and the first-round pick has done an admirable job operating Sean Payton's scheme as a rookie quarterback. But something's ...

A rematch of last year's NFC Championship Game, the Detroit Lions vs. San Francisco 49ers was expected to be one of the best games of the season when the schedule was released. Now though ...

Purdy had completed a 17-yard pass to Jauan Jennings to the 49ers’ 47-yard line just before the two-minute warning with the 49ers trailing 22-17. They had all their timeouts, George Kittle ...