The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating ...

Coffee doesn’t just perk up your brain, it might be flipping important switches inside your cells, too. While known for ...

Scientists have developed a new molecule that can deliver powerful immune-activating treatment directly to cancer cells, ...

A breakthrough brain scan shows Parkinson’s drugs can misfire in the brain, helping some patients less than others. The fix?

Panelists discuss how chronic neuroinflammation involves distinct mechanisms from acute relapses—including microglial ...

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the ...

The latest research published in Genes & Diseases unveils groundbreaking insights into the role of the aging process and the ...

This is a useful study in the role of CHI3L1 in Kupffer cells, the macrophages of the liver, showing that CHI3L1 alters glucose regulation in obesity. Specifically, Chi3l1 protects glucose-dependent ...

Preventing an overabundance of microglial activation is crucial in managing SCI. SIRT1 as a NAD-dependent deacetylase has the effect of ameliorating SCI, but its mechanism of action in microglia ...

In short, preclinical models may not necessarily permit the detection of context-specific activation of PI3K (or other effectors) by mutant KRAS.

Activation of PI3Ka also led to regeneration of nerves in a mouse model of peripheral nerve injury. Aside from these uses outside of cancer, and potential new cancer indications, there has been work ...