This was a randomised controlled trial that evaluated the effectiveness of clinical and radiographic outcomes of modified pulpotomy (MP) in immature permanent teeth with apical periodontitis (AP), ...

[10] IL-1β might also play a role in the initiation and up-regulation of the inflammatory response in apical periodontitis by increasing the levels of IL-6 and prostaglandin E2 production.

Periodontal disease is a prevalent global dental health issue that significantly affects a large number of individuals. This severe gum infection damages the soft tissue and erodes the bone ...

Periodontitis is highly prevalent worldwide. It is characterized by periodontal attachment and alveolar bone destruction, which not only leads to tooth loss but also results in the exacerbation of ...

In addition, intracanal metformin for apical periodontitis has therapeutic efficacy. It can suppress lipopolysaccharide (LPS)-induced inducible nitric oxide synthase (iNOS) and NO production by ...