ACROBiosystems has developed a series of specialized proteases for the screening and validation of ADC linkers, focusing on ...

The new study looks at how consuming vitamin B-12 led to a cascade of signals originating in the brain and triggering actions ...

CHICAGO — In this video, Paolo F. Caimi, MD, MBA, staff physician at Cleveland Clinic, discusses the phase 2/3 WaveLINE-003 trial of patients with relapsed/refractory diffuse B-cell lymphoma ...

Background Chronic inflammation and elevated reactive oxygen species are key contributors to hepatocellular carcinoma (HCC) ...

This valuable manuscript investigates the localisation of nutrient receptors in bloodstream stage trypanosomes, with implications for both nutrient uptake and immune evasion. Results after direct ...

The field of cellular immunotherapy has undergone a profound transformation in recent years, with autologous chimeric antigen receptor (CAR) T-cell therapies emerging as the standard-of-care option ...

Over the past decade, several novel immunotherapies have transformed the treatment landscape of relapsed or refractory B-cell acute lymphoblastic leukaemia. In the pivotal TOWER trial, blinatumomab—a ...

During cell-to-cell spread, HIV-1 protease activity triggers CARD8 inflammasome activation and IL-1β release from macrophages, which may contribute to inflammation and chronic immune activation.

Officials at the University of Chicago Crime Lab's Policing Leadership Academy brought in members of storied improv theater ...

T cell interacting with a functionalized micropillar platform. Confocal z-stack image a T cell on the 0.5-4-0.5 surface, showing the cell membrane in red, nucleus in blue and the pillar surface in ...